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The Effects of the mouthrinses containing fluoride and xylitol on the microhardness of tooth enamel and the reduction of halitosis

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Abstract

°á·Ð
ÀúÀÚµéÀº, 0.02% ºÒÈ­³ªÆ®·ý¹èÇÕ¾çÄ¡¾×°ú 0.05% ºÒÈ­³ªÆ®·ý¹èÇÕ¾çÄ¡¾× ¹× 10% ÀÚÀϸ®Åç
-0.02%ºÒÈ­³ªÆ®·ý¹èÇÕ¾çÄ¡¾×ÀÇ ¹ý¶ûÁúÇ¥¸é¹Ì¼¼°æµµº¯È­¸¦ ÃøÁ¤ °ËÅäÇÏ°íÀÚ, Ä¡¿­ÀÌ ºñ±³Àû
°í¸£°í ¿ì½Äº´¼Ò°¡ ¾ø´Â 10¸íÀÇ ¼ºÀÎ ³²³à¸¦ ½ÇÇè´ë»óÀÚ·Î ¼±Á¤ÇÏ°í, 3§®Á÷°æÀÇ Ä¡¾Æ½ÃÆíÀ»
pH 4.0À¸·Î Á¶Á¤µÈ 0.1M lactic acid-sodium hydroxide buffer¿ë¾×¿¡ Àá±âµµ·Ï ÇÏ¿© 37¡É¿¡
¼­ 39½Ã°£µ¿¾È Żȸ½ÃŲ ÈÄ, ½ÇÇè´ë»óÀÚÀÇ ÇϾǿ¡ ÀûÇÕÇϵµ·Ï Á¦ÀÛµÈ ±¸°­³»À¯ÁöÀåÄ¡ÀÇ ¼³
¸é¿¡ °¢ 3°³¾¿ °íÁ¤ÇÏ¿´À¸¸ç, À¯ÁöÀåÄ¡¸¦ ±¸°­³»¿¡ ÀåÂøÇÏ¿© °¢°¢ÀÇ ½ÇÇè¿ë¾× 10§¢¸¦ 30ÃÊ
°£ ¾çÄ¡ÇÑ ÈÄ 1½Ã°£ µ¿¾È À¯ÁöÀåÄ¡¸¦ ±¸°­³»¿¡¼­ Á¦°ÅÇÏÁö ¸øÇϵµ·Ï ÇÏ¿´°í, ÀÌ·¯ÇÑ °úÁ¤À»
1ÀÏ 2ȸ 1ÁÖ°£ ½Ç½ÃÇÏ¿´´Ù. 1ÁÖÈÄ ¸ðµç ½ÃÆíÀ» äÃëÇÏ¿©, microhardness tester(Shimadzu
corporation Model, HMV-2000 No. 33100410, Japan)·Î½á ½ÇÇè´ë»ó¾çÄ¡¿ë¾×º° Ä¡¾Æ½ÃÆí¹ý¶û
ÁúÇ¥¸é¹Ì¼¼°æµµ¸¦ ÃøÁ¤ ºñ±³ °ËÅäÇÏ¿´´Ù. ¶ÇÇÑ, µ¿ÀÏÇÑ ½ÇÇè´ë»ó¾çÄ¡¾×ÀÇ ±¸Ãë°¨¼ÒÈ¿°ú¸¦ °Ë
ÅäÇÏ°íÀÚ, 10¸íÀÇ ½ÇÇè´ë»óÀÚ¿¡°Ô 0.5gm¾¿ÀÇ ¸¶´ÃÀ» ÀúÀÛÇÏ°Ô ÇÏ¿©, ¹ß»ýµÈ È£±âÁßÀÇ ±¸Ãë
°¨Áö¼ººÐÀÎ ¸ÞÆ¿¸ÓĸźÀÇ ¾çÀ» ¾çÄ¡¾×»ç¿ëÀü°ú »ç¿ëÈÄ 5ºÐ, 10ºÐÀÌ °æ°úÇÑ ÈÄ °¢°¢ ÃøÁ¤ÇÏ
¿©, ½ÇÇè´ë»ó¾çÄ¡¾×»ç¿ëÀüÀÇ ¸ÞÆ¿¸Óĸź¾çÀ» ±âÁØÀ¸·Î ±¸Ãë°¨¼ÒÀ²À» »êÃâÇÏ¿© ½ÇÇè´ë»ó¾çÄ¡
¾×»ç¿ë±ºº° ±¸Ãë°¨¼ÒÈ¿°ú¸¦ ºñ±³ °ËÅäÇÏ¿©, ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
1. 0.02% NaF ¹èÇÕ¾çÄ¡¾×»ç¿ë±ºÀÇ ¾çÄ¡¾×»ç¿ëÀüÈÄÀÇ ¹ý¶ûÁú°æµµ´Â Åë°èÇÐÀûÀ¸·Î À¯ÀÇÇÑ
Â÷ÀÌ°¡ ÀÎÁ¤µÇÁö ¾Ê¾ÒÀ¸³ª(P>0.05), 0.05% NaF ¹èÇÕ¾çÄ¡¾× »ç¿ë±º°ú 10% Xylitol-0.02%
NaF ¹èÇÕ¾çÄ¡¾×»ç¿ë±º¿¡¼­´Â ¾çÄ¡¾×»ç¿ëÀüÈÄÀÇ ¹ý¶ûÁú°æµµ°¡ Åë°èÇÐÀûÀ¸·Î À¯ÀÇÇÑ Â÷ÀÌ°¡
ÀÎÁ¤µÇ¾ú´Ù(P<0.05).
2. ½ÇÇè´ë»ó¾çÄ¡¾×»ç¿ëÀüÈĹý¶ûÁú°æµµÀÇ º¯È­·®Àº 0.02% NaF ¹èÇÕ¾çÄ¡¾×»ç¿ë±º¿¡¼­ º¸´Ù
0.05% NaF ¹èÇÕ¾çÄ¡¾×»ç¿ë±º°ú 10% Xylitol-0.02% NaF ¹èÇÕ¾çÄ¡¾×»ç¿ë±º¿¡¼­ ´õ ³ôÀº ¹ý
¶ûÁúÇ¥¸é¹Ì¼¼°æµµÀÇ Áõ°¡¾ç»óÀ» ³ªÅ¸³»¾úÀ¸³ª Åë°èÇÐÀûÀ¸·Î À¯ÀÇÇÑ Â÷ÀÌ°¡ ÀÎÁ¤µÇÁö´Â ¾Ê¾Ò
´Ù(P>0.05).
3. ¸¶´Ã¼·ÃëÈÄ 5ºÐ¿¡ È£±âÁßÀÇ ¸ÞÆ¿¸Óĸź¾çÀÇ º¯È­À²Àº 10% Xylitol-0.02% NaF ¹èÇÕ¾ç
Ä¡¾×»ç¿ë±º¿¡¼­ °¡Àå ¸¹ÀÌ °¨¼ÒµÇ¾úÀ¸¸ç, ´Ù¸¥ µÎ ±ºÀÇ ¸ÞÆ¿¸Óĸź¾çÀÇ º¯È­À²°ú Åë°èÇÐÀû
À¸·Î À¯ÀÇÇÑ Â÷ÀÌ°¡ ÀÎÁ¤µÇ¾ú´Ù(P<0.05).
4. ¸¶´Ã¼·ÃëÈÄ 10ºÐ¿¡ È£±âÁßÀÇ ¸ÞÆ¿¸Óĸź¾çÀÇ º¯È­À²Àº 10% Xylitol-0.02% NaF ¹èÇÕ¾ç
Ä¡¾×»ç¿ë±º¿¡¼­ °¡Àå ¸¹ÀÌ °¨¼ÒµÇ¾úÀ¸³ª, ´Ù¸¥ µÎ ±ºÀÇ ¸ÞÆ¿¸Óĸź¾çÀÇ º¯È­À²°ú Åë°èÇÐÀû
À¸·Î À¯ÀÇÇÑ Â÷ÀÌ°¡ ÀÎÁ¤µÇÁö´Â ¾Ê¾Ò´Ù(P>0.05).

The microhardness changes of tooth enamel by mouthrinses was investigated in vivo
using acrylic mandibular removable appliance. Three different mouthrinses which
contained 1) 0.02% NaF 2) 0.05% NaF 3) 0.02% NaF+10% Xylitol were tested. Early
caries-like lesions were created using 0.1M lactic acid-sodium hydroxide buffer(pH 4.0).
Three enamel specimens with early caries-like lesions were mounted into the recesses
of lingual surface of the appliance with sticky wax. 10 subjects wore the appliance for
one hour after mouthrinsing two times per day. Each subjects wore the appliance for
three separate 7-days period; 0.02% NaF mouthrinse, 0.05% NaF mouthrinse, 0.02%
NaF+10% Xylitol mouthrinse. Solace microhardness were checked by microhardness
tester(Shimadzu corporation Model, HMV-2000 No. 33100410, Japan) before and after
mouthrinse.
In order to evaluate the elect of mouthrinses on reducing halitosis, the author had
analysed the volatile sulfur compounds(VSC) in halitosis after the chewing of 0.5gm
garlic powder by 10 subjects. Following mouth air sampling immediately after the
chewing of garlic powder, subjects used mouthrinses and reevaluated at 5 and 10
minutes after chewing of garlic powder. The evaluation of methylmercaptan in mouth air
was done by gas chromatographic technic. The percent change in methylmercaptan
concentration of air samples were calculated in relation to values of mouth air sample
immediately after chewing of garlic powder.
The obtained results were as follows :
1. The change of surface microhardness in 0.02% NaF mouthrinse group did not
showed significantly between before and after mouthrinse(P>0.05), but surface
microhardness in 0.05% NaF mouthrinse group and in 0.02% NaF and 10% Xylitol
mouthrinse group showed significantly between before and after mouthrinse(P<0.05).
2. The change of surface microhardness was higher in 0.05% NaF mouthrinse group
and in 0.02% NaF and 10% Xylitol mouthrinse group than in 0.02 %NaF mouthrinse
group, but there was no significance statistically.
3. The mouthrinse containing 0.02% NaF and 10% Xylitol reduced more
methylmercaptan than other experimental mouthrinses at 5 minutes after the chewing of
garlic powder (P<0.05).

Å°¿öµå

ºÒÈ­³ªÆ®·ý; ÀÚÀϸ®Åç; ¾çÄ¡¾×; ¹ý¶ûÁúÇ¥¸é¹Ì¼¼°æµµ; ±¸Ãë; mouthrinse; microhardness; halitosis; fluoride; xylitol;

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